You should be good to go with this combo, although you will want to be sure you have an aux transmission cooler. Did your truck come with a factory tow package? If so, the cooler will be part of that package.
My Explorer has a 4.6L small V-8, and in the high country, I describe it as "adequate". Your 4.10 rear end will help, but don't expect miracles. The problem isn't steep grades, as much as it is the lack of air at altitude. My Explorer begins to feel it at about 7,000-8,000 feet. By the time I get to 10K, it is struggling.
My preference is to hold the RPM to 4,000 or less (red line is 6,000) and let the road speed fall where it may, rather than trying to maintain some given road speed at the expense of flogging the engine. But that's just me - I'm pretty conservative about this stuff (and since my Explorer has 135,000 miles and is still going strong, it seems to have worked).
Bill
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