Maybe, BUT, they are still trailer tires and per Goodyear are only speed rated at 75mph.  I had the 2 original tires on my 98 blow (neither Carlisle or Goodyear).  Found blisters on one Carlisle and replaced it with a Goodyear.  Have 3 Carlisle tires but never actually had one blow.  In the future I will buy truck tires.  The reasons for a "trailer" tire don't make sense.  We are not towing a 5th wheel or an 8' high conventional trailer.  Those produce leveraged sway which requires a stiffer sidewall.  Since a full size 13 passenger van is taller than a TrailManor and it can use truck tires, I can see no problem as long as the truck tire is the same size and load range as the original on the TrailManor.