The biggest difference that I enjoy (from my old PU) is not having to squat under the bed platforms and push them up with my back to put the bed-support-poles in the bumper. I just simply couldn't do it any more.
Putting the TM roofs up & down is nothing compared to cranking up that top (with an AC on it).
No more messing with canvas support braces, lowering that door into place and messing with the lift-up galley sink.
I suppose if you are in your 30's or 40's, these aren't issues but when you get into your 60's they become a bit of a pain.
The thing that I really love is that after having to get out of the CG before noon, we don't have to stop at a fast food place on the way home
. We just find a nice spot, pull off the road, set-up (without unhitching) and enjoy a meal from our own home. It saves $, saves time and we get a beautiful view in the package. We're only 5 minutes away from being a TT at any given moment.